Extended Data Fig. 3: Measurements of inter-RBD distance on Spike trimer.

Structure of SARS-CoV-2 Spike trimer (PDB: 6VSB)³². RBD colored in blue is in the ‘up’ position while RBDs colored in green and pink are in the ‘down’ position. Distance between the mid-points of the ACE2 binding interface (PDB: 6M17)¹ on respective RBDs was measured in Pymol.