Extended Data Fig. 7: mTOR inhibitors suppress ferroptosis.
From: A compendium of kinetic modulatory profiles identifies ferroptosis regulators
a, Cell death determined using STACK in three different cell lines. Results are mean ± SD from three independent experiments. b, 4E-BP1 protein phosphorylation and total levels. Blot is representative of three independent experiments. c, Total glutathione (GSH + GSSG) levels measured using Ellman’s reagent (DNTB). d, System xc- activity inferred from glutamate release over 2 h from HT-1080 and U-2 OS cells treated as indicated. e, Cell death determined using STACK. Results in c-e are from three independent experiments.
