Extended Data Fig. 5: KDM2B affects cell growth through SULF1.
From: Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate
a, Sanger sequencing of a A375 KDM2B SULF1 double knock-out clone (KDM2BC5 SULF1#1) after targeting with the indicated sgRNA. Both sequence changes result in frameshift mutations. b, Clonogenic assay under normal growth conditions. After 14 days, colony growth was quantified by methylene blue staining and absorption readings at 650 nm (t-test, n = 3). Scale bar = 5 mm.
