Extended Data Fig. 3: Cryo-EM density map for NK1R-miniGs/q70 heterotrimeric complex.
From: Selective G protein signaling driven by substance P–neurokinin receptor dynamics
(a) Unsharpened Cryo-EM density map for individual NK1R helices and Substance P density as determined by extending a 2.5 Å radius away from each modeled atom. Local resolution estimation of unsharpened Cryo-EM density maps for (b) SP-NK1R-miniGs/q70 and (c) SP6-11-NK1R-miniGs/q70 heterotrimeric complex from cryoSPARC. SP and SP6-11 density are highlighted in and shown at equivalent enclosed volume thresholds.
