Extended Data Fig. 3: Structural analysis of BpLGDH.
From: Metabolism of a hybrid algal galactan by members of the human gut microbiome
a, structure of the BpLGDH dimer with one monomer shown in cartoon and the other as a solvent accessible surface. The putative catalytic histidine is shown in blue. b, overlap of BpLGDH (blue) with AKR11C1 from Bacillus halodurans (grey, PDB ID 1YNP). c, overlap of the BpLGDH (blue) active site with the active site of AKR11C1 (grey). Conserved residues, including the putative catalytic histidine (H119 in AKR11C1), are shown as sticks. In panels c and d the NADPH bound to AKR11C1 is shown in stick representation.
