Extended Data Fig. 8: Tyr284 is conserved in SalC homologs.
From: Enzymatic assembly of the salinosporamide γ-lactam-β-lactone anticancer warhead
Condensed alignment showing conservation of Tyr284 in all SalC homologs from Salinispora and Streptomyces cinnabarigriseus JS360 (CinC) but not in canonical elongating KSs. All SalC homologs from Salinispora strains found in JBI IMG database. For functional KS sequences refer to Supplementary Figure 5.
