Extended Data Fig. 3: Comparison of allosteric sites of CB1 with that in other GPCRs (PAR2 and GPR40).
From: Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1
(a) Analysis of sequence conservation in PAM site of CB1. (b) Structural comparison of PAM bound CB1 with allosteric modulator AZ3451 bound PAR2 (5NDZ). (c) Structural comparison of PAM bound CB1 with TAK-875 bound GPR40 (4PHU).
