Extended Data Fig. 9: Box plots showing the influence of unknown modification mass error on the molecular formula (MF) inference.
From: A modification-centric assessment tool for the performance of chemoproteomic probes
The number of MF candidates for light and heavy modifications (n=60) derived from18 tested probes were calculated to meet the allowable error ranges (ppm value from 1 to 20). Note that when the error belongs to 1.26 ppm (the median mass accuracy achieved by pChem, highlighted in red), the number of MF candidates is typically less than three, and when the error comes to 2.95 ppm (the median mass accuracy achieved by FragPipe, highlighted in blue), more candidate MFs will be generated. Elements of each box plot indicate the median (orange line segment), the 25th and 75th percentiles (lower-end and upper-end of the box, respectively), and the 1.5x interquartile range (whiskers).
