Extended Data Fig. 10: TRPV2 desensitization is accelerated by E2.
From: Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands
a, representative whole-cell recordings of TRPV2 activation and desensitization by 2-APB alone or with E2 (dots in green or orange, respectively) in calcium-free solution. An exponential function is fitted to the desensitization time course to determine the time constant. b, comparison of the desensitization time constant of TRPV2 by 2-APB in the presence or absence of E2 (n = 3-5 cells). Data were presented as mean ± s.e.m. Two-tailed t-test was performed. *, p = 0.0441 in t-test.
