Extended Data Fig. 4: Correlation analysis of calculated versus measured growth rates.
From: Deep mutational scan of a drug efflux pump reveals its structure–function landscape
Growth rates for 28 individual variants relative to wild-type EfrCD were determined in the presence of ethidium as two biological replicates. Each growth rate data point is the average of at least two technical replicates. Theoretical growth rates were calculated based on variant scores (see Methods). a, b, Pearson correlation analysis of measured versus calculated growth rates for the two biological replicates, respectively. c, List of analyzed variants and the corresponding calculated and measured growth rates.
