Extended Data Fig. 6: Single strain peptide display experiments validate non-cathelicidin activators identified in the sort-seq screen. | Nature Chemical Biology

Extended Data Fig. 6: Single strain peptide display experiments validate non-cathelicidin activators identified in the sort-seq screen.

From: An E. coli display method for characterization of peptide–sensor kinase interactions

Extended Data Fig. 6: Single strain peptide display experiments validate non-cathelicidin activators identified in the sort-seq screen.The alternative text for this image may have been generated using AI.

PhoPQ activation is reported via the PvirK-mNG plasmid. Strains in which human AMP activators are displayed in KB1 are shown in black. Control strains in which human AMP activators are displayed in KB1 PhoQ H277A are shown in grey. Positive (LL-37) and negative (no peptide) peptide display controls in KB1 are shown in red and blue, respectively. Each plot contains data collected over n = 3 separate days, with results from each day shown as a separate marker.

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