Extended Data Fig. 2: Most PhoQ-activating AMPs are not toxic when displayed on the E. coli outer membrane. | Nature Chemical Biology

Extended Data Fig. 2: Most PhoQ-activating AMPs are not toxic when displayed on the E. coli outer membrane.

From: An E. coli display method for characterization of peptide–sensor kinase interactions

Extended Data Fig. 2: Most PhoQ-activating AMPs are not toxic when displayed on the E. coli outer membrane.The alt text for this image may have been generated using AI.

Endpoint OD600 measurements for KB1 and KB1 PhoQ H277A in response to IPTG induction of surface-displayed AMPs. A negative control strain expressing the SLAY peptide display system without an appended peptide cargo (no-peptide) is shown. Measurements were performed after 4.5 h growth from an initial culture OD600 of 0.0001. Data was collected over n = 3 separate days, with results from each day shown as a separate marker.

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