Extended Data Fig. 4: Comparison of 7-mer complex with EXT1-2, 4-mer complex, and EXT1-2 complexed with UDP-GlcA.
From: Structural basis for heparan sulfate co-polymerase action by the EXT1–2 complex
a, Superimposition of EXT1-2, 4-mer and 7-mer complex. b, Orthogonal view highlighting the GT-A fold comparison. 7-mer complex colored the same as in Fig. 1, EXT1-2 in light gray, and 4-mer complex in wheat. c, Superimposition of EXT1 GT-B fold from EXT1-2 complexed with UDP-GlcA and 7-mer complex. 7-mer complex are colored the same as in Fig. 1, and EXT1-2 complexed with UDP-GlcA in cyan. Residues involved in active pocket are shown as sticks.
