Extended Data Fig. 6: Photo-ANA enables the identification of host-pathogen protein-protein interactions during infection.
From: Photo-ANA enables profiling of host–bacteria protein interactions during infection
a, Schematic of ‘forward’ experiment to identify PipB2-interacting host proteins during infection using photo-ANA. In ‘reverse’ experiments, ‘heavy’ and ‘light’ cells were swapped. b, PPI network of identified PipB2-interacting host proteins generated by STRING v.11.5. Thickness of edges denotes confidence of interaction. Node color depicts k-mean clusters. Edges in dash line indicate interactions between clusters. c, Colocalization analysis of PipB2 and FLOT1-GFP signal in Fig. 4e. R indicate Pearson’s correlation coefficient. M1 and M2 indicate Mander’s overlap coefficient for PipB2 and FLOT1-GFP, respectively.
