Extended Data Fig. 5: Crystal structure of KDM2A bound to H3K36-UNC8015 peptide covalent conjugate.
From: Structural basis of paralog-specific KDM2A/B nucleosome recognition
a, Structure of KDM2A catalytic domain in complex with H3K36C-UNC8015. b, Identical view of structure of KDM2A catalytic domain in complex with H3K36me2 peptide and α-ketoglutarate (α-KG). c-e, Zoomed views of c, H3K36C-UNC8015 peptide, d, H3K36me2 peptide and α-KG, and e, overlayed aligned structures. f, 2Fo-Fc electron density map of H3K36C-UNC8015 peptide at 1σ.
