Extended Data Fig. 3: SULT1B1 cannot sulfate the H3Y99 in the assembled histone H3 in nucleosome variants.
From: Histone tyrosine sulfation by SULT1B1 regulates H4R3me2a and gene transcription
(a) to (c), SULT1B1 cannot sulfate the H3Y99 in the assembled histone H3 in nucleosome variants. The simulated structure of active SULT1B1 binding with octameric (from PDB ID: 5GSE) (a), hexametric (from PDB ID: 5GSE) (b) and tetrameric nucleosomes (PDB ID: 4Z2M) (c) were performed, respectively. The steric clashes between the simulated structure of active SULT1B1 (green) and the histone H3-containing complexes (red) were highlighted in yellow.
