Fig. 4: NPARC across cell lines. | Nature Chemical Biology

Fig. 4: NPARC across cell lines.

From: Deep thermal profiling for detection of functional proteoform groups

Fig. 4

a, Exemplary fits of the null (top) and alternative (bottom) models to the cell line melting profiles of NEK2_0, the only proteoform found for NEK2. b, Volcano plot of the results obtained from the differential analysis. Black points represent proteoforms with the top 10% of F-statistics taken as differentially melting across cell lines (F ≥ P90%(F)). c, Melting profile of DNTT_1 across cell lines color-labeled by B cell developmental stage. d, Melting profile of INPP4B_1 across cell lines color-labeled by cell line genomic aberration subtype.

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