Extended Data Fig. 3: Robustness of experimental data and comparisons of the effect of endogenously expressed Dro and Api variants on cell growth.
From: Inhibition of translation termination by the antimicrobial peptide Drosocin
a, Correlation of the depletion scores of E. coli clones from the single amino acid Dro mutant libraries generated on the bases of pDro[UAG] or pDro[UGA] expression plasmids. Pearson correlation coefficient (r) is indicated. b, Depletion scores of library clones endogenously expressing single-amino acid Dro variants from the pDro[UGA] plasmids. Coloring is according to the toxic effects (blue - highly toxic, yellow - mildly toxic, salmon - not toxic). The analogous data for the pDro[UAG] library are shown in Fig. 4. c, Similarly calculated depletion scores for endogenously expressed Api mutants from the pApi plasmid using data from the reference7.
