Extended Data Fig. 4: Location and binding mode of heme in different CydDC conformations.
From: Dissecting the conformational complexity and mechanism of a bacterial heme transporter
(a) Local density map of \({{{\mathbf{IF}}}}_{{{{\mathrm{asym}}}}}^{{{{\mathrm{apo}}}}}\), \({{{\mathbf{IF}}}}_{{{{\mathrm{bound}}}}}^{{{{\mathrm{heme}}}}}\), \({{{\mathbf{IF}}}}_{{{{\mathrm{coordinated}}}}}^{{{{\mathrm{heme}}}}}\), and \({{{\mathbf{IF}}}}_{{{{\mathrm{confined}}}}}^{{{{\mathrm{heme}}}}}\) at the heme binding site shown in side and cross-section views. (b) Heme models fitted into corresponding densities in maps of each conformational state. Density features of heme highlight that the heme molecule is rigidified during the process of binding and confinement.
