Extended Data Fig. 9: Transmembrane helix rearrangement during the proposed heme release mechanism. | Nature Chemical Biology

Extended Data Fig. 9: Transmembrane helix rearrangement during the proposed heme release mechanism.

From: Dissecting the conformational complexity and mechanism of a bacterial heme transporter

Extended Data Fig. 9

Center: side views of CydDC TMH regions during heme confinement and release toward the periplasm. Left: cross-section views of TMH conformations at the level of the heme-binding site. Right: cross-section views of TMH conformations at the level of the periplasmic gate. Distances between TMs 1 and 6 of CydD and CydC (critical for gate opening and closing) are indicated. Periplasmic loop regions are omitted for clarity.

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