Extended Data Fig. 3: Local stereo views of CroT in complex with CMP, and of the SH3b domain in complex with polymer. | Nature Chemical Biology

Extended Data Fig. 3: Local stereo views of CroT in complex with CMP, and of the SH3b domain in complex with polymer.

From: A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule

Extended Data Fig. 3: Local stereo views of CroT in complex with CMP, and of the SH3b domain in complex with polymer.The alternative text for this image may have been generated using AI.

a, Model of CroT (orange ribbons) in complex with CMP, glycerol, and phosphate and the corresponding electron density map displayed at 1 RMSD. b, Local density map for the CMP, glycerol, and phosphate found in CroT. c, Model of selected SH3b domain (tan-colored ribbons) in complex with DP2 (dimer of Hib capsule polymer) displaying the overall density map at 1 RMSD. d, Density map for the DP2 ligand. The density for ribose, ribitol, and phosphate allows the unambiguous placing of the DP2 and helped determine the orientation of the polymer.

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