Extended Data Fig. 4: Alignment of the dimeric structures of FUT9 and HpFucT. | Nature Chemical Biology

Extended Data Fig. 4: Alignment of the dimeric structures of FUT9 and HpFucT.

From: Structural basis for Lewis antigen synthesis by the α1,3-fucosyltransferase FUT9

Extended Data Fig. 4: Alignment of the dimeric structures of FUT9 and HpFucT.The alternative text for this image may have been generated using AI.

(a) The homodimeric structures of FUT9 (green and gray cartoons for chains A and B, respectively) and HpFucT (orange and cyan cartoons for chains A and B, respectively) were aligned based on the conserved donor domain structures for the respective chain A of each homodimer. The respective individual homodimeric structures of (b) HpFucT and (c) FUT9 (two views rotated by 70°) are shown with the two-fold axes as indicated. The two-fold axis of FUT9 requires a 70° rotation relative to the HpFucT in order to display the 2-fold axis indicating a distinct interface region for the monomers in the respective homodimers.

Back to article page