Extended Data Fig. 5: Cytosine base editing with CjCas9 and evoCjCas9 on sites in the Pcsk9 locus.
From: Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility
Editing frequency (C-to-T) with eAID or TadCDd CBEs with one or two C-terminal UGI domains in Neuro-2a cells. Bars represent mean with error bars representing standard error of the mean of three independent biological replicates performed on separate days (n = 3), unless otherwise noted. Individual data points as black dots.
