Extended Data Fig. 2: Indel formation with CjCas9 and evoCjCas9 on endogenous target sites.
From: Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility
a,b, Indel frequencies of CjCas9 and evoCjCas9 on 14 non-canonical and 10 canonical PAM sites in HEK293T cells with selection harvested 9 days (a) or without selection 4 days (b) post transfection. Bars (a, b) represent mean with error bars representing standard error of the mean of three independent biological replicates performed on separate days (n = 3). Individual data points as black dots.
