Extended Data Fig. 7: Cryo-EM data analysis of the eIF2BδL516A structure. | Nature Chemical Biology

Extended Data Fig. 7: Cryo-EM data analysis of the eIF2BδL516A structure.

From: A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling

Extended Data Fig. 7

(a) Representative micrograph showing the quality of data used for the final reconstruction of the eIF2BδL516A structure. A total of 4042 micrographs were acquired and analyzed. (b) Data processing scheme of the eIF2BδL516A structure. (c) Fourier shell correlation (FSC) plots of the 3D reconstructions of eIF2BδL516A unmasked (dark blue), masked (orange). (d) Orientation angle distribution of the eIF2BδL516A reconstruction. (e) Local resolution map of the eIF2BδL516A structure.

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