Extended Data Fig. 3: Coverage and redundancy results from HDX-MS experiments.
From: A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling
(a) coverage and redundancy at each eIF2B residue for peptides included in all conditions of the comparative apo eIF2B vs NSs-bound eIF2B vs eIF2-P-bound eIF2B experiment. Solid colored bars indicate each eIF2B subunit, corresponding to color scheme in Fig. 1. Shown are peptides from one representative experiment; all HX experiments were replicated at least 3 independent times.
