Extended Data Fig. 1: Chemical structures of AGs referenced in our study and used for antimicrobial susceptibility testing. | Nature Chemical Biology

Extended Data Fig. 1: Chemical structures of AGs referenced in our study and used for antimicrobial susceptibility testing.

From: Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance

Extended Data Fig. 1

AGs are grouped according to structural subclass with carbons colored to distinguish substitution pattern of 2-DOS ring when present. (a) atypical subclass. (b) 4,6-disubstituted AGs. Kanamycin A and B differ at the 2’ position highlighted in red. Amikacin and plazomicin differ at the N6’ position (red highlight), but both contain the same substituent at N1. (c) 4,5-disubstituted AGs.

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