Extended Data Fig. 6: Relative abundances of N-acylspermidines detected in mouse liver, brain, and heart samples.
From: Acylspermidines are conserved mitochondrial sirtuin-dependent metabolites
N-acylspermidine levels did not significantly differ between WT and Sirt5 KO samples, except for a decrease of maspid#3 (N8-glutaryl) and maspid#5 (N8-succinyl) in the Sirt5 KO brain samples. Data represent total peak intensity in each sample, based on detected peak area and sample volume, per tissue weight. Mice were all female. n = 5, except for WT mouse brain, n = 4. Data are mean ± s.d. and P values were calculated using unpaired, two-tailed t-tests with Welch correction (P ≥ 0.1 are not shown).
