Extended Data Fig. 4: Cryo-EM density of tRNA in the P site represents a tRNAi-specific structural feature.
From: Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1
(a) Schematic diagram of tRNAi (left) and an elongator tRNAMet (right) for depicting the differences between the two tRNA species that charge methionine. (b) A close-up view of G31 and C39 base-pairing in the cryo-EM reconstruction. The density fits well to an atomic model of tRNAi, rather than the elongator tRNAMet, which has two pseudouridines in the corresponding nucleotide positions (ψ31 and ψ39).
