Half a century after its discovery, platelet-activating factor (PAF) is now recognized as a ferroptosis-activating phospholipid that contributes to tubule cell damage and nephron loss in acute kidney injury.
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B.P. is co-founder and shareholder of ROSCUE Therapeutics GmbH.
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Zheng, J., Proneth, B. Chains of death. Nat Chem Biol 20, 799–800 (2024). https://doi.org/10.1038/s41589-023-01541-w
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DOI: https://doi.org/10.1038/s41589-023-01541-w
