Extended Data Fig. 8: MPV ligand densities in representative OFS, INT1, INT2, and INT3 cryo-EM reconstructions. | Nature Chemical Biology

Extended Data Fig. 8: MPV ligand densities in representative OFS, INT1, INT2, and INT3 cryo-EM reconstructions.

From: Antiviral drug recognition and elevator-type transport motions of CNT3

Extended Data Fig. 8: MPV ligand densities in representative OFS, INT1, INT2, and INT3 cryo-EM reconstructions.

Cryo-EM densities around the nucleoside binding site from representative reconstructions containing OFS, INT1, INT2, or INT3 protomers (reconstructions used: OFS-INT1-INT1 highest res; INT1-INT1-INT1 ‘condition 1’ ensemble analysis; INT2-INT2-INT2 ‘condition 2’ ensemble analysis; INT1-INT1-INT3 ‘condition 1’ ensemble analysis). Sharpened maps shown (threshold = 6σ).

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