Extended Data Fig. 5: Analysis of SP-reporter screen.
From: Global signal peptide profiling reveals principles of selective Sec61 inhibition
a, Comparison of biophysical features of sensitive and resistant SPs (see Methods). Data are presented as box plots, the center line indicated the median, upper to lower bounds indicates 75th and 25th percentile, respectively. b, Heat map of amino acid enrichment scores at the indicated positions of KZR-9873-sensitive-SPs, calculated as described in Fig. 2f and Methods. c, Histograms showing N- and C-region length distributions for the SPs analyzed in (a, b).
