Extended Data Fig. 8: The nuclease-independent off-target analysis of IminiBEs, SIminiBEs and SpGn-BEs.
From: Engineering miniature IscB nickase for robust base editing with broad targeting range
a, Nuclease-independent DNA off-target analysis of C-to-T editing efficiencies induced by IminiCBE, SIminiCBE and SpGn-CBE using the R-loop assay by dSaCas9. b, Nuclease-independent DNA off-target analysis of A-to-G editing efficiencies induced by IminiABE, SIminiABE and SpGn-ABE using the R-loop assay by dSaCas9. All data are means ± s.d. (n = 3 independent experiments).
