Advanced E2-modified ubiquitin probes enable investigation of E2-selective ubiquitination in cells and the discovery of tyrosine ubiquitination as a modification occurring in a UBE2D3-specific manner.
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Jones, H.B.L., Damianou, A. & Kessler, B.M. Tracking E2-specific substrates. Nat Chem Biol 21, 976–977 (2025). https://doi.org/10.1038/s41589-025-01848-w
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DOI: https://doi.org/10.1038/s41589-025-01848-w