Poly(ester amide)s (PEAs) have various applications but their synthesis is currently limited to chemical methods. Now, the biosynthesis of various PEAs in engineered Escherichia coli is presented. The PEAs incorporate different amino acid monomers in varying fractions, which influences their physical, thermal and mechanical properties.
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This is a summary of: Chae, T. U. et al. Biosynthesis of poly(ester amide)s in engineered Escherichia coli. Nat. Chem. Biol. https://doi.org/10.1038/s41589-025-01842-2 (2025).
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A bacterial platform for the bio-based production of poly(ester amide)s. Nat Chem Biol 21, 1134–1135 (2025). https://doi.org/10.1038/s41589-025-01859-7
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DOI: https://doi.org/10.1038/s41589-025-01859-7
