Extended Data Fig. 7: (related to Fig. 2) Transcriptome analysis of GBC subpopulations selected by Kinprola labeling.
From: Molecular recording of cellular protein kinase activity with chemical labeling
(a) Heatmap of DEGs from three Kinprolaon-labeled GBC subpopulations, color-coded by Z-score. Genes in the GO term ‘mitotic cell cycle process’ are in magenta; DEGs shared with KinprolaPKA are in gray. (b) First principal coordinate analysis of the three Kinprolaon-expressing groups. (c–e) GO term enrichment for KinprolaPKA (c) and Kinprolaon (d, e) DEGs, ranked by FDR. (f) Venn diagram showing overlap between KinprolaPKA- and Caprola6-identified DEGs. (g, h) GO terms for overlapping DEGs from (f), ranked by FDR.
