Table 1 Genome-sequenced ‘Entotheonella’ phylotypes and their host sponges analyzed in previous work or the current study (specified in column 1). Further details can be found in Supplementary Table 1
From: Chemical richness and diversity of uncultivated ‘Entotheonella’ symbionts in marine sponges
Sponge (suborder) | Known compounds (numbers in parentheses refer to representative structures in Fig. 1 and Supplementary Fig. 1) | Symbiont variants (E. refers to ‘Entotheonella’, P. to ‘Proxinella’) |
|---|---|---|
T. swinhoei Y (Astrophorina); previous studies | Konbamide (2), keramamides (3), nazumamide A (4), pseudotheonamides (5), cyclotheonamide (6), onnamides and theopederins (7), polytheonamides (8), aurantosides and sterols | ‘Ca. E. factor’ TSY1 ‘Ca. E. gemina’ TSY2 ‘Ca. E. arcus’ YB-1 |
T. swinhoei YB (Astrophorina); this study | See above | ‘Ca. E. factor’ TSYB1 ‘Ca. E. gemina’ TSYB2 ‘Ca. E. mitsugo’ TSYB3 |
T. swinhoei WA (Astrophorina); previous study | Theonellamides (9) and misakinolides (10) | ‘Ca. E. serta’ TSWA1 |
T. swinhoei WB (Astrophorina); this study | Theonellamides (9) and swinholides (11) | ‘Ca. E. serta’ TSWB1 ‘Ca. E. consors’ TSWB2 |
Theonella sp. 1 BA (Astrophorina); this study | Unknown | ‘Ca. E. melakyensis’ TCBA1 ‘Ca. E. serta’ TCBA2 |
Theonella sp. 2 BT (Astrophorina); this study | Unknown | ‘Ca. E. symbiotica’ BT01 ‘Ca. E. inquilina’ BT02 ‘Ca. E. melakyensis’ BT03 ‘Ca. E. catenata’ BT04 |
D. calyx (Astrophorina); this study | Calyculins (12), kasumigamide (13), calyxamides (14), indole derivatives and cyclodipeptides | ‘Ca. E. armillaria’ DC1 |
D. kiiensis (Astrophorina); this study | Discodermins (15–19), lipodiscamides (20) | ‘Ca. E. monilis’ DK1 |
D. dissoluta (Astrophorina); this study | Discodermolides | ‘Ca. E. tacita’ DD1 ‘Ca. E. baccata’ DD2 ‘Ca. E. tertia’ DD3 |
A. cribrophora (Spirophorina); this study | Unknown | ‘Ca. P. opulenta’ AC1 |
