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Engineered biomaterials

Self-assembling information-processing biomaterial circuits

Nature Chemical Biology volume 21, pages 1839–1841 (2025)Cite this article

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The construction and assembly of information-processing biomaterials are limited by the need for laborious assembly of various circuits. A new framework to assemble protein-based elements encoding complex Boolean operations enables user-defined release of biomolecules from these materials.

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Fig. 1: Design of self-assembling functional information-processing circuits.

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Authors and Affiliations

  1. Leibniz Institute for New Materials (INM), Saarbrücken, Germany

    Rosanne Schmachtenberg & Wilfried Weber

  2. Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg, Freiburg, Germany

    Rosanne Schmachtenberg & Wilfried Weber

  3. Faculty of Biology, University of Freiburg, Freiburg, Germany

    Rosanne Schmachtenberg

  4. Saarland University, Department of Materials Science and Engineering, Saarbrücken, Germany

    Wilfried Weber

Authors
  1. Rosanne Schmachtenberg
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  2. Wilfried Weber
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Correspondence to Wilfried Weber.

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The authors declare no competing interests.

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Schmachtenberg, R., Weber, W. Self-assembling information-processing biomaterial circuits. Nat Chem Biol 21, 1839–1841 (2025). https://doi.org/10.1038/s41589-025-02071-3

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