Extended Data Fig. 2: Human and mouse peritoneal immune cell composition is different.
(a) UMAP projection of all CD45+ cells sequenced from the peritoneal cavity of 7 adults and 3 C57BL6 mice, forming 30 distinct clusters (colored as shown in the legend), with cluster names assigned based on inferred function. (b) UMAP plots showing the distinct immune cell composition of the mouse (right) and human (left) peritoneal cavity. Colors are coded as in a. (c) Feature plots demonstrating the expression of key immune cell markers, including markers for T and B lymphocytes and myeloid cells. Color scale represents the normalized gene expression. (d) Proportion of each cluster out of total immune cells for each sample, grouped by species (n = 7 human adult samples and n = 3 mouse samples). Bars depict means with error bars representing standard deviation. Multiple two-tailed t-tests followed by false discovery rate (FDR) correction; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, n.s. not significant. The exact p-values and FDR corrected q-values are reported as Source Data.
