Extended Data Fig. 1: Basic characteristics of the integrated dataset and signature genes of 25 peripheral immune cell subsets covering 13 age groups.

a. UMAP plots showing the 25 peripheral immune cell subsets covering 13 age groups across the entire lifespan. Cell subsets are indicated in different colors. b. UMAP plots showing the distribution of expression of selected signature genes for 25 cell subsets. c. UMAP plots showing the distribution of expression of selected signature genes for 12 T cell subsets. d. Violin plots showing the distribution of expression of selected signature genes for 25 cell subsets. e. Violin plots showing the distribution of UMI counts (left panel) and gene counts (right panel) per cell type. B_BCR+GNLY+ cells are circled with dashed circle in (a) and (b).