Extended Data Fig. 10: REV-ERBαβ deficiency reshapes the chromatin landscape of metabolism-related genes in ILC3s. | Nature Immunology

Extended Data Fig. 10: REV-ERBαβ deficiency reshapes the chromatin landscape of metabolism-related genes in ILC3s.

From: Circadian circuits control plasticity of group 3 innate lymphoid cells by sustaining epigenetic configuration of RORγt

Extended Data Fig. 10: REV-ERBαβ deficiency reshapes the chromatin landscape of metabolism-related genes in ILC3s.The alternative text for this image may have been generated using AI.

a, Heatmap showing key metabolism related genes from scRNA-seq in Fig. 5a. b-f, Washington University Epigenome Browser display of pseudobulk scATAC clusters [Zfp683+ ILC1, Gzma+ ILC1, tILC3, WT (NKp46+, DN, CCR6+) ILC3s and DKO (NKp46+, DN, and CCR6+) ILC3s] of Ucp2 (b), Lpl (c), Pkm (d), Ass1 (e), and Acat1 (f), alongside REV-ERBα and NFIL3 ChIP-seq. Differentially accessible regions are marked with discontinuous boxes.

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