Fig. 5: Age and prior pregnancies modify genital ILC subsets distribution.
a, Spearman correlation of percentage of ILCs in mononuclear cells with age in the EM (n = 31), END (n = 21) and ECT (n = 22). b,c, Correlation of percentage of ILC1s (b) and ILC3s (c) in each tissue (EM, n = 31; END, n = 20; ECT, n = 22). d, Comparison of the percentage of ILCs in mononuclear cells between donors with and without prior pregnancies (EM, n = 30; END, n = 21; ETC, n = 21). e, Correlation of the percentage of ILCs in mononuclear cells in each tissue with time since last pregnancy. f, Correlation of percentage of CD161+ ILCs in each tissue with time since last pregnancy (pregnant: EM, n = 22; END, n = 13; ECT, n = 15; never-pregnant: EM, n = 6; END, n = 6; ECT, n = 6). g, Correlation of percentage of CD161+ ILCs in each tissue age (EM, n = 23; END, n = 18; ECT, n = 15). h, Comparison of CD161 expression between never-pregnant and previously pregnant patients (1+ pregnancies: EM, n = 23; END, n = 15; ECT, n = 15; no pregnancies: EM, n = 6; END, n = 6; ECT, n = 6). Each dot represents a different individual. Horizontal lines represent the median ± IQR. Spearman rank test for all correlations; non-parametric Mann–Whitney U-test for comparisons of two groups. All tests were two-sided.
