Extended Data Fig. 8: LC-Mo like macrophages show pro-fibrotic signature. | Nature Immunology

Extended Data Fig. 8: LC-Mo like macrophages show pro-fibrotic signature.

From: A distinct monocyte transcriptional state links systemic immune dysregulation to pulmonary impairment in long COVID

Extended Data Fig. 8

a, Blood (cohort 5) CD14+, CD16+ Monocytes and monocyte derived DCs from independent cohort (GSE263817)23 b, Gene expression profile of clusters showing LC-Mo/MC4 like genes in cluster5. (c) Proportion of blood and BAL Monocyte/Macrophage cells in each of the cluster as described in Fig. 6d. d, Gene expression as described in (GSE263817)23 for Tissue resident Alveolar Macrophages (TRAM) and monocyte derived Macrophages(moAM) e, Gene expression profile derived from Wendisch et al. 33 of CI1-CI6 clsuters as shown in Fig. 6df, Proportion of cells in either CI4, CI5 or CI6 clusters from each donor classified into PASC categories.

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