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COVID-19

Immunologically distinct long COVID after mild acute disease

Distinct monocyte gene expression programs were identified in people with long COVID after mild-to-moderate COVID-19 versus severe acute COVID-19, providing evidence that immunological dysregulation after mild acute COVID-19 may be the result of distinct pathobiological pathways.

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Fig. 1: Unique immunological signatures in individuals with long COVID following mild-to-moderate SARS-CoV-2 infection.

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Correspondence to Annukka A. R. Antar.

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Antar, A.A.R., Pasetes, E.C., Brennon, K.M.Z. et al. Immunologically distinct long COVID after mild acute disease. Nat Immunol (2026). https://doi.org/10.1038/s41590-025-02399-x

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