Extended Data Fig. 10: Overarching model of the interactions between TGF-β, IFNs and IL-6 and their downstream TFs. | Nature Immunology

Extended Data Fig. 10: Overarching model of the interactions between TGF-β, IFNs and IL-6 and their downstream TFs.

From: TGF-β mediates epigenetic control of innate antiviral responses and SIV reservoir size

Extended Data Fig. 10: Overarching model of the interactions between TGF-β, IFNs and IL-6 and their downstream TFs.

The interaction of TGF-β, IFNs and IL-6 and their downstream TFs directed the expression of epigenetics modifiers and antiviral ISGs, resulting in the dichotomic phenotype of CA-vDNAhi and CA-vDNAlo RMs. Created in BioRender. Pereira ribeiro, S. (2026) https://BioRender.com/ult0x4p.

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