Extended Data Fig. 5: Continuous exposure to cow’s milk does not induce tolerance to BLG in germ-free mice fed with water or Enfamil and sensitized with BLG plus cholera toxin. | Nature Medicine

Extended Data Fig. 5: Continuous exposure to cow’s milk does not induce tolerance to BLG in germ-free mice fed with water or Enfamil and sensitized with BLG plus cholera toxin.

From: Healthy infants harbor intestinal bacteria that protect against food allergy

Extended Data Fig. 5: Continuous exposure to cow’s milk does not induce tolerance to BLG in germ-free mice fed with water or Enfamil and sensitized with BLG plus cholera toxin. The alt text for this image may have been generated using AI.

a, Change in core body temperature at indicated time points following first challenge with BLG of mice fed with water (n = 12) or Enfamil (n = 10) collected from 3 independent experiments. b–d, serum BLG-specific IgE (b), BLG-specific IgG1 (c) and mMCPT-1 (d) from mice in a. For a, circles represent mean, and error bars represent s.e.m. For b–d, circles represent individual mice, and bars represent mean + s.e.m. Linear mixed-effect models were used to compare groups in a and two-sided Student’s t-test in b–d after log transformation. **P < 0.01. n.s. = not significant (P = 0.36).

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