Extended Data Fig. 2: Overview of BACTGs.
From: Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity
An overview of the BACTG deletion series generated indicating the length of the reporter gene and the measured luciferase activity for mice crossed to Lepob/Lepob mice, fed, or fasted for 48 h. ob eWAT/iWAT: −22 to +8.8 (n = 3), −17.4 to +8.8 (n = 7), −16.5 to +8.8 (n = 10), +762 to +13.9 (n = 3), +762 to +14.2 (n = 4), +762 to +14.8 (n = 3), +762 to +15.8 (n = 6), +762 to +18 (n = 2 or 3); fed eWAT/iWAT: −22 to +8.8 (n = 8), −17.4 to +8.8 (n = 13), −16.5 to +8.8 (n = 12), −16.4 to +8.8 (n = 2), −16.1 to +8.8 (n = 11), −762 to +8.8 (n = 7), +762 to +13.6 (n = 14), +762 to +13.9 (n = 3), +762 to +14.2 (n = 9), +762 to +14.8 (n = 3), +762 to +15.8 (n = 3), +762 to +18 (n = 5 or); fasted eWAT/iWAT: −22 to +8.8 (n = 6), −17.4 to +8.8 (n = 4), −16.5 to +8.8 (n = 11), +762 to +13.9 (n = 2), +762 to +14.2 (n = 11), +762 to +14.8 (n = 3), +762 to +15.8 (n = 3), +762 to +18 (n = 3). Values are means ± s.e.m.
