Extended Data Figure 7: Inherent correlations between cell subsets.
From: A clinically meaningful metric of immune age derived from high-dimensional longitudinal monitoring
Boxplots denote ages at which cell subsets reached their corresponding attractor point frequencies stratified by either cell subset (median interquartile range of 14.75 years; naive CD8+ T cells were excluded as most individuals did not reach the attractor point frequencies; n = 72 individuals) (a) or individuals (median interquartile range of 2 years; n = 10 cell subsets) (b). Boxes represent 25th and 75th percentiles around the median (line). Whiskers, 1.5× interquantile range. c, Scheme describing longitudinal correlations calculated between every pair of cell subsets. d, Longitudinal pairwise Spearman correlations between cell subsets are indicated by circle color whereas circle size corresponds to P value (calculated by permutations; only correlations (P < 0.05) are shown; n = 69 individuals).
