Extended Data Fig. 4: Immunotherapeutic bacteria limit tumor growth in syngeneic mouse models of melanoma and triple-negative breast cancer.
From: Programmable bacteria induce durable tumor regression and systemic antitumor immunity
a, Relative body weight of B16-F10-bearing C57BL/6 mice over time. Mice were treated with PBS (n = 4 mice), eSLC (n = 5 mice), miap301 (n = 5 mice) or eSLC–CD47nb (n = 6 mice) (P < 0.05, two-way ANOVA with Tukey’s multiple comparisons test). Data are mean ± s.e.m. b, Individual tumor growth trajectories of subcutaneous 4T1 tumors after intratumoral injection of eSLC (n = 7 tumors) or eSLC–CD47nb (n = 8 tumors); related to data shown in Fig. 2f. c, Individual tumor growth trajectories of subcutaneous B16-F10 melanoma after intraperitoneal injection of miap301 or intratumoral injection of PBS, eSLC or eSLC–CD47nb; related to data shown in Fig. 2h.
