Extended Data Fig. 2: K. pneumoniae susceptibility to perinatal antibiotics that alter diversity of the neonatal intestinal microbiome.
From: Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis
(a) Growth inhibition disk diffusion assay showing antibiotic susceptibility of Kp-39 (left) and (right) to vancomycin (30ug) or gentamicin (10ug) grown under aerobic or anaerobic conditions. Bars display mean ± SD. No inhibition detected, nd. Data representative of 3 similar experiments; n = 3 plates per condition tested. (b) Beta-diversity (upper panel) and alpha-diversity (lower panel) measurements from microbiome communities of P5 pups reared with or without maternal antibiotics. Lines display mean ± SD. Beta-diversity and alpha-diversity metrics were calculated from the microbiome sequencing data described in Fig. 3a.
